OncoPanel™ Multiplexed Tumor Cell Cytotoxicity

OncoPanel™

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Using our OncoPanel testing service, you can:

Rapidly gain mechanistic information regarding the cytotoxic and chemotherapeutic potential of your compounds
Select up to four cytotoxic measures to be assessed simultaneously by whole cell imaging
Investigate multiple types of cancers and multiple mutations to determine specificity and selectivity
Test compounds in our pre-validated cell lines or send your own cell lines

Gain more chemotherapeutic potential information in less time. Parse out the most relevant mechanism of cell death.

Mechanism	Marker
Cell Proliferation	Relative cell count
Apoptosis	Activated Caspase-3
Mitosis	Phospho-Histone H3
Necrosis	Propidium Iodide or 7-Amino-Actinomycin Iodide

Service Features

Flexible testing protocols
Timely data delivery
Fully validated and quality-controlled
Expert scientific and technical support for data interpretation
Non-contact dispensing automation system for compound addition, cell fixing and immunostaining
Test at 24, 48 or 72 hours
15 cell lines in 5 cancer types available for routine assay
Experience with hundreds of cell lines
Primary and normal cell lines also available
Custom cell lines can be cryo-preserved for repeat screening

Choose from multiple cell lines and multiple mutations for a custom data output.

Cell Line Gene Mutations^*

Cell Line

BRC-
ABL

CDK
N2A

PDG
FRA

TP
53

EGFR

KRAS

NRAS

ER+

PIK
3CA

RB1

MAD
H4

PTEN

STK
II

bRAF

BRC
A2

CTN
NB1

APC