MDS Pharma Services offers a novel approach to functional receptor pharmacology analysis by providing access to the MDS Sciex CellKey™ platform utilizing cellular dielectric spectroscopy (CDS) to enable functional pharmacology testing for most classes of receptor targets and signal transduction paths, including G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs).
Service Features
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Custom functional pharmacology screening capabilities to identify potential endogenous receptor sources for novel targets, or putative ligands for orphan receptors
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Validated panel of CellKey™ catalog assays for activity confirmation and potency testing
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Assays are performed in an intact cellular environment providing a physiologically relevant context for compound testing
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Label-free technology provides confidence that expected pharmacology is preserved
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