Automated Image Analysis
Nuclei are shown in red. p65 NF-κB is in green. Image masks are labeled in blue for nuclei and red for cytoplasm.
| NF-κB Activation Inhibitor |
481406 |
>100µM |
| NF-κB Activation Inhibitor II, JSH-23 |
481408 |
>100µM |
| NF-κB Activation Inhibitor III |
481411 |
>100µM |
| IKK Inhibitor II, Wedelolactone |
401474 |
>100µM |
| IKK Inhibitor III, BMS-345541 |
401480 |
3.9µM |
| SN50 |
481480 |
>30µM |
| Bay 11-7082 |
196870 |
22.2µM |
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MDS Pharma Services Advantage
- Cell-based assay for more physiologically relevant output
- Minimum compound consumption for 384 well plate format
- Automated, robust and cost-effective
- Accelerated throughput screening (900 compounds per week)
- Objective, consistent and fast
Service Features
- Compound testing in HeLa or HUVEC cell lines
- Direct visualization and automated quantitation of NF-κB
- Minimum compound requirements due to 384 well plate formats and non-contact acoustic energy based compound addition
- A reference compound included as a control on each plate
- 4 week turnaround time
Contact Us
for additional HCA based assay information.
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